Synergism of Adipocytokine Profile and ADIPOQ/TNF-α Polymorphisms in NAFLD-associated MetS Predict Colorectal Liver Metastases Outgrowth
نویسندگان
چکیده
منابع مشابه
Colorectal liver metastases.
BACKGROUND Despite major advances in therapies for liver metastases, colorectal cancer remains one of the commonest causes of cancer-related deaths in the UK. SOURCES OF DATA The international literature on the management of colorectal liver metastases (CLM) was reviewed. AREAS OF AGREEMENT Due to a combination of highly active systemic agents and low perioperative mortality achieved by hig...
متن کاملColorectal liver metastases
Each year in the UK, between 1214 000 people develop liver metastases from colorectal cancer. These metastases will contribute to the death ofthe patient in about 80% ofcases. Treatments aimed at these tumours are best administered when the tumour is small. Current investigative methods allow tumours as small as 0.5 mm to be detected, and should be offered to all colorectal cancer patients at r...
متن کاملColorectal Liver Metastases
The diagnosis and management of CRLM is complex and requires a multidisciplinary team approach for optimal outcomes. Over the past several decades, the 5-year survival following resection of CRLM has increased and the criteria for resection have broadened substantially. Even patients with multiple, bilateral CRLM, previously thought unresectable, may now be candidates for resection. Two-stage h...
متن کاملTreatment of colorectal liver metastases
Colorectal cancer (CRC) is the third most common cancer in the word. Liver metastasis is the most common site of colorectal metastases. The prognosis of resectable colorectal liver metastases (CRLM) was improved in the recent years with the consideration of chemotherapy and surgical resection as part of the multidisciplinary management of the disease; the current 5-year survival rates after res...
متن کاملBiology of colorectal liver metastases.
The elucidation of the interaction of the tumor and its microenvironment has increased surgeons' understanding of the biologic mechanisms mediating metastases formation. The ability to develop effective biologic therapies will depend on understanding the complex interactions among endothelial cells and tumor cells and on the cytokine cross-talk among all cells within a particular tumor at a par...
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ژورنال
عنوان ژورنال: Cancer Genomics - Proteomics
سال: 2019
ISSN: 1109-6535,1790-6245
DOI: 10.21873/cgp.20154